Castillo was ordained on Oct. 15, 1983, in the Diocese of Corpus Christi after attending a minor seminary for three years. His wife also participated with him. A Mass was celebrated at St. Paul Parish on Nov. 8 by Bishop Emeritus William Higi, with celebrants Father Richard Weisenberger and Father Mark Walter. A social followed in the parish hall with ethnic foods brought in by different communities. Entertainment was provided by Latino children and dancers from St. Ambrose Parish in Anderson, Ind. Attendees included residents from multiple neighboring cities.
Deacon Castillo is the associate for the Latino community in St. Paul Parish. He has worked with 10 other parishes in the Diocese of Lafayette for the past 22 years. He is a member for the Society of Our Lady of the Most Holy Trinity Religious Order and is assigned to the migrant ministry throughout the Diocese of Lafayette which covers north-central Indiana.
Castillo left his home in Beeville for Indiana in 1991. He and his wife have several children, Domingo Castillo Jr. and Diana Quiroga, both of Bee County, and David Castillo, Daniel Castillo and Deana Vice, all of Indiana; and several grandchildren, Samuel Castillo, Victor and Alejandro Quiroga, Troy Vice and Austin, Aidan and Blake Castillo.